• 1 January 1979
    • journal article
    • research article
    • Vol. 360  (7) , 833-840
Abstract
The CNBr peptide .alpha.1-(III)CB4 comprises the sequence region from position 403-551 of the .alpha.1(III) chain. Almost the entire sequence of this region was elucidated using 2 hydroxylamine- and 1 chymotrypsin [EC 3.4.21.1]-derived fragments for automated Edman degradation. The sequence analysis of .alpha.1(III)CB4 was completed with the help of trypsin [EC 3.4.21.4] and 1 protease V8[Staphylococcus aureus]-derived peptide. Comparison with the corresponding region of the .alpha.1(I) chain revealed a striking homology between the 2 chains in this region which is higher than for the entire .alpha. chains.