Surface-Induced Dissociation of Multiply Protonated Peptides
- 1 November 1992
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Society for Mass Spectrometry
- Vol. 3 (8) , 859-862
- https://doi.org/10.1016/1044-0305(92)80010-i
Abstract
We report here surface-induced dissociation spectra of three multiply charged peptides: doubly protonated angiotensin I, doubly protonated renin substrate, and triply protonated melittin. For comparison, the collision-activated dissociation spectra of renin substrate and melittin are also presented. The spectra show that surface-induced dissociation provides structural information on multiply charged peptides at the picomole per microliter sample concentrations compatible with electrospray ionization. For multiply protonated angiotensin I, renin substrate, and melittin, surface collisions (l00-165 eV) favor a limited number of fragmentation pathways, which are the same as those favored in collision-activated dissociation experiments.This publication has 20 references indexed in Scilit:
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