ORTHOSTATIC CIRCULATORY FAILURE ("GRAVITY SHOCK") IN THE DOG
- 1 April 1944
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 141 (2) , 227-234
- https://doi.org/10.1152/ajplegacy.1944.141.2.227
Abstract
Anesthetized dogs, suspended in the upright (feet down) position for 20 min. to 4 hrs., show varying degrees of hypotension, progressive hemoconc. and marked increases in arterio-venous O2 and CO2 differences. After 10-20 min., the plasma protein level diminishes while the protein conc. of lymph increases. These changes can be reversed by returning the animals to the horizontal position and approx. control values are achieved in 30 min. Animals kept in the upright position are extremely sensitive to hemorrhage. Irreversible circulatory failure is often precipitated by the withdrawal of relatively small quantities of blood (30-50 cc). This can usually be prevented and the response to tilting improved by the infusion of saline and/or blood during the upright period.This publication has 5 references indexed in Scilit:
- The influence of posture on the pulmonary blood volume and the alveolar gas tensionsThe Journal of Physiology, 1943
- PHYSIOLOGICAL STUDY OF THE VERTICAL STANCE OF MANPhysiological Reviews, 1943
- THE PRESENT STATUS OF THE SHOCK PROBLEMPhysiological Reviews, 1942
- EFFECT OF GRAVITY ON THE BLOOD PRESSURE OF THE DOGAmerican Journal of Physiology-Legacy Content, 1941
- THE EFFECTS OF DECREASED BLOOD OXYGEN AND INCREASED BLOOD CARBON DIOXIDE ON THE FLOW AND COMPOSITION OF CERVICAL AND CARDIAC LYMPHAmerican Journal of Physiology-Legacy Content, 1940