EFFECT OF OILY VEHICLE ON OCULAR PILOCARPINE CONCENTRATION
- 1 August 1979
- journal article
- research article
- Published by Wiley in Acta Ophthalmologica
- Vol. 57 (4) , 633-636
- https://doi.org/10.1111/j.1755-3768.1979.tb00510.x
Abstract
The effect of 1.4% polyvinyl alcohol (PVA) vehicle and castor oil vehicle on ocular pilocarpine concentration was studied by radioactive method in the rabbit eye. Statistically higher radioactivities were measured from the anterior surface structures of the eyes dropped with oily vehicle when compared to PVA vehicle at 120 min. The conjunctiva and the cornea serve as a drug reservoir for the long-lasting drug effect after oily pilocarpine drops.Keywords
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