THE EFFECT OF THE INTRAVENOUS ADMINISTRATION OF DEXTRAN ON CARDIAC OUTPUT AND OTHER CIRCULATORY DYNAMICS 1

Abstract
Five normal men were given 500 cc. of 6% dextran. Pulmonary artery and femoral artery pressures were followed closely with an electromanometer, and cardiac output detns. were made before and after dextran administration. Dextran consistently increased the blood volume proportionately to the amt. administered and that the effect was prolonged. Cardiac output was increased in every case. The increased blood volume was associated with prolonged elevations of pressure in the pulmonary artery.

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