Results of in vitro sperm penetration tests in cervical mucus in the normal cycle and in mucus under the influence of the contraceptive pill
- 1 January 1975
- journal article
- research article
- Published by Springer Nature in Archiv für Gynäkologie
- Vol. 218 (3) , 227-232
- https://doi.org/10.1007/bf00667383
Abstract
Women who are either menstruating normally or taking a combined or sequential preparation for hormonal contraception were examined at intervals of 2 days with reference to the day of the cycle. The parameter studied was thein-vitro penetrability of the cervical mucus for sperms. Whilst the combined preparation completely blocked the cervical canal for the spermatozoa, the distance travelled by the spermatozoa under the influence of the sequential preparation was approximately the same as in the normal cycle. This study of the depth of penetration of the spermatozoa in relation to the hormonal situation was prompted not by contraceptive but rather by epidemiological considerations of cervical carcinoma. Abhängig vom Zyklustag wurden in zweitägigem Abstand Frauen untersucht, die normal menstruierten, ein Emphasenoder Zweiphasenpräparat zur hormonalen Kontrazeption einnahmen. Geprüft wurde die Pentrierbarkeit des Cervixsekretes für Spermienin vitro. Während das Einphasenpräparat den Cervicalkanal für Samenzellen völlig blockiert, entspricht der Raumgewinn unter der Einnahme des Zweiphasenpräparates etwa den Verhältnissen im normalen Zyklus. Anlaß für die Kontrolle der Tiefenpenetration des Spermas abhängig von der hormonalen Situation waren nicht contrazeptive, sondern epidemiologische Überlegungen zum Cervixcarcinom.Keywords
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