Caveolae--Not Just Craters in the Cellular Landscape
- 24 August 2001
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 293 (5534) , 1447-1448
- https://doi.org/10.1126/science.1061079
Abstract
Caveolae are small invaginations in the plasma membrane of mammalian cells that seem to be important for signal transduction and uptake of macromolecules. According to Shin and Abraham in their Perspective, recent work reveals that these cellular craters have been commandeered by pathogens and bacterial toxins, enabling them to gain entry to host cells while avoiding the perils of classic endocytosis and the lysosomal degradation pathway.Keywords
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