An optimized semi-automatic rate method for serum glutathione reductase activity and its application to patients with malignant disease.
Open Access
- 1 January 1976
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 29 (1) , 73-77
- https://doi.org/10.1136/jcp.29.1.73
Abstract
An improved and optimized method for serum glutathione reductase is described. The reference range for normal subjects is 47-79 IU/1. The method is more sensitive than conventional enzyme tests in the detection of malignant disease. It was not raised more frequently in patients with clinical evidence of metastases than in those clinically free of such metastases, and it did not seem to correlate with prognosis among those patients who failed to survive six months from the time the analysis was first conducted.Keywords
This publication has 17 references indexed in Scilit:
- A new colorimetric method for the determination of NADH/NADPH dependent glutathione redugtase in erythrocytes and in plasmaClinica Chimica Acta; International Journal of Clinical Chemistry, 1975
- Automated reaction rate analysis of erythrocyte glucose-6-phosphate dehydrogenase and glutathione reductase activitiesBiochemical Medicine, 1974
- Red Cell Glutathione and Glutathione Reductase in Cystic FibrosisExperimental Biology and Medicine, 1973
- Effect of flavin compounds on glutathione reductase activity: in vivo and in vitro studiesJournal of Clinical Investigation, 1969
- Enzymatic test for the detection of a riboflavin deficiency. NADPH-dependent glutathione reductase of red blood cells and its activation by FAD in vitroCellular and Molecular Life Sciences, 1968
- A serum alkaline phosphatase isoenzyme of human neoplastic cell origin.1968
- A Series of New Screening Procedures for Pyruvate Kinase Deficiency, Glucose-6-Phosphate Dehydrogenase Deficiency, and Glutathione Reductase DeficiencyBlood, 1966
- Increased erythrocyte glutathione reductase activity in diabetes mellitusBiochemical and Biophysical Research Communications, 1961
- Published by Wiley ,1959
- GLUTATHIONE REDUCTASE ACTIVITY IN BLOOD AND BODY FLUIDS1Journal of Clinical Investigation, 1958