• 1 January 1977
    • journal article
    • research article
    • Vol. 21  (2) , 97-103
Abstract
In chick embryo cells (CEC) and plasma membranes (PM) isolated therefrom, 3 forms of cyclic[c]AMP phosphodiesterase (PDE) were demonstrated: PDE activated only by Ca2+ (Ca-PDE), PDE activated only by Mg2+ (Mg-PDE) and PDE stimulated in the presence of 2 mM Mg2+ by low concentrations of Ca2+ (Ca-Mg-PDE). Purified influenza A virus, under suitable conditions, lowered the activities of these PDE. The decrease was greater in samples incubated in the presence of ATP than in those incubated in its absence.