INFLUENCE OF SALMONELLA PULLORUM INFECTION ON VARIOUS LIVER TRICARBOXYLIC ACID ENZYMES AND CITRATE LEVELS IN THE CHICK

Publisher Website
Google Scholar
Abstract
Citric acid concentrations were measured in livers of normal chicks, with and without fluoroacetate treatment, and in chicks infected with S. pullorum, with and without fluoroacetate treatment. Citrate accumulated during the terminal phase of the disease in infected chicks. In non-infected, fluoroacetate-treated chicks, citrate levels rose shortly after introduction of the inhibitor and subsequently declined. In infected, fluoroacetate-treated chicks, the metabolite increased during the 1st 12 hours, then subsided, and again increased slightly during the terminal phase of infection. Infection caused varying degrees of impairment of the liver tricarboxylic acid enzymes assayed during the course of the disease.