Transactivation of Vascular Endothelial Growth Factor (VEGF) Receptor Flk-1/KDR Is Involved in Sphingosine 1-Phosphate-stimulated Phosphorylation of Akt and Endothelial Nitric-oxide Synthase (eNOS)
Open Access
- 1 November 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (45) , 42997-43001
- https://doi.org/10.1074/jbc.m204764200
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Sphingosine 1-Phosphate and Isoform-specific Activation of Phosphoinositide 3-Kinase βJournal of Biological Chemistry, 2001
- Sphingosine 1-phosphate receptorsProstaglandins & Other Lipid Mediators, 2001
- Sphingosine 1‐Phosphate Activates Erk‐1/‐2 by Transactivating Epidermal Growth Factor Receptor in Rat‐2 CellsIUBMB Life, 2000
- Sphingosine 1-Phosphate Activates Erk-1/-2 by Transactivating Epidermal Growth Factor Receptor in Rat-2 CellsIUBMB Life, 2000
- A Novel Function of VEGF Receptor-2 (KDR): Rapid Release of Nitric Oxide in Response to VEGF-A Stimulation in Endothelial CellsBiochemical and Biophysical Research Communications, 1999
- The Akt kinase signals directly to endothelial nitric oxide synthaseCurrent Biology, 1999
- VEGF Induces Nuclear Translocation of Flk-1/KDR, Endothelial Nitric Oxide Synthase, and Caveolin-1 in Vascular Endothelial CellsBiochemical and Biophysical Research Communications, 1999
- Nitric oxide synthase modulates angiogenesis in response to tissue ischemia.Journal of Clinical Investigation, 1998
- Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptorsNature, 1996
- Hypertension in mice lacking the gene for endothelial nitric oxide synthaseNature, 1995