A systems view of mRNP biology
Open Access
- 1 December 2004
- journal article
- review article
- Published by Cold Spring Harbor Laboratory in Genes & Development
- Vol. 18 (23) , 2845-2860
- https://doi.org/10.1101/gad.1256904
Abstract
Gene expression occurs through a complex mRNA-protein (mRNP) system that stretches from transcription to translation. Gene expression processes are increasingly studied from global perspectives in order to understand their pathways, properties, and behaviors as a system. Here we review these beginnings of mRNP systems biology, as they have emerged from recent large-scale investigation of mRNP components, interactions, and dynamics. Such work has begun to lay the foundation for a broader, integrated view of mRNP organization in gene expression.Keywords
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