Oestrogen and progesterone receptors in lentigo maligna
- 1 January 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 118 (1) , 69-71
- https://doi.org/10.1111/j.1365-2133.1988.tb01751.x
Abstract
We have measured oestrogen and progesterone binding in specimens of histopathologically confirmed lentigo maligna (LM) lesions excised from five elderly white men, using a dextrancoated charcoal method. Oestrogen binding was observed in four of the five specimens, and progesterone binding in all five. Marginal normal skin showed only non-specific binding for oestrogen and progesterone. The presence of steroid hormone receptors in LM suggests the possibility that hormone responsiveness may be relevant in the transformation of a lentigo maligna into malignant melanoma.This publication has 11 references indexed in Scilit:
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