Administration of the Hyperglycemic-Glycogenolytic Factor of the Pancreas to Non-Anesthetized and Anesthetized Subjects

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Abstract
The intraven. injn. of a purified prepn. of the hyperglycemic factor of the pancreas produces an increase in the venous blood sugar of man. This response is variable in quantity and is not increased by increased dosage. The production of anesthesia enhances the increase in venous blood sugar produced by the hyperglycemic factor. This effect of anesthesia is attributed to an increase in peripheral blood flow rather than to an augmented hyperglycemic effect.

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