Decrease of Radiation Damage to Chromosomes by DNA and Deoxyribonucleotides

Abstract
Chromosomal aberrations in cultured [calf-liver] cells were chosen as a parameter to study the influence of DNA and its constituent deoxyribonucleotides. Native DNA provides a marked decrease in aberration yield after x-irradiation, as do equimolar solutions of DNA precursors. Of these, only deoxyadenylic and deoxyguanylic acid proved effective if added together to the cells. No such effect was afforded by single deoxyribonucleotides or by RNA precursors.