A computer programme for estimation of genetic risk in X linked disorders, combining pedigree and DNA probe data with other conditional information.
Open Access
- 1 February 1986
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 23 (1) , 40-45
- https://doi.org/10.1136/jmg.23.1.40
Abstract
A computer programme is presented for calculating the recurrence risk in X linked disorders, combining pedigree and DNA probe data with other conditional information such as carrier detection tests. The methods of computation are shown in the given examples. The programme can be used with either a single DNA probe or two 'flanking' DNA probes for both familial and isolated case pedigrees. For isolated case families the mutation rate at the disease locus can be taken into account in conjunction with the DNA probe data.This publication has 8 references indexed in Scilit:
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