A Direct Comparison of Noninvasive Coronary Angiography by Electron Beam Tomography and Navigator-Echo-Based Magnetic Resonance Imaging for the Detection of Restenosis Following Coronary Angioplasty

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Abstract
Ropers D, Regenfus M, Stilianakis N, et al. A direct comparison of noninvasive coronary angiography by electron beam tomography and navigator-echo-based magnetic resonance imaging for the detection of restenosis following coronary angioplasty. Invest Radiol 2002;37:386–392. To compare electron beam tomography (EBT) with MR imaging (MRI) for detection of restenosis after coronary angioplasty (PTCA). One hundred eighteen patients after PTCA were investigated. By EBT, 50 axial images were acquired (3-mm slice thickness, 120–160 mL radiographic contrast agent). MRI was performed using respiratory-gated sequences (24–48 cross-sections, 2-mm slice thickness, 20 mL Gd-DTPA). EBT and MRI images were evaluated concerning high-grade post-PTCA restenosis (≥70%) and validated against coronary angiography. In EBT, 28 patients and in MRI, 31 patients were not evaluable. In the remaining patients, sensitivity for restenosis detection was 90% in EBT (17/19) and 73% in MRI (11/15;P = 0.370). In EBT, specificity was significantly higher (66% vs. 49%, P = 0.043). Overall accuracy was 71% for EBT and 53% for MRI (P = 0.014). For the detection of high-grade restenosis after PTCA, EBT demonstrated significantly higher accuracy than MRI.