ACUTE FENITROTHION POISONING

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  • 1 January 1977
    • journal article
    • research article
    • Vol. 116  (4) , 377-379
Abstract
A technician was accidentally exposed to the organophosphorus insecticide fenitrothion and subsequently treated with pralidoxime for the autonomic, somatic and psychiatric manifestations of intoxication. Although long-term therapy with pralidoxime is not recommended, this patient required and obtained symptomatic benefit from its prolonged use. Erythrocytic acetylcholinesterase [E.C. 3.1.1.7] and plasma pseudocholinesterase [E.C. 3.1.1.8] activities had been monitored prior to exposure and were monitored throughout treatment and following recovery. Continual monitoring of cholinesterase activities of individuals occupationally exposed to organophosphorus ester insecticides and early diagnosis are essential.