Mechanisms Responsible for Catalysis of the Inhibition of Factor Xa or Thrombin by Antithrombin Using a Covalent Antithrombin-Heparin Complex
Open Access
- 1 June 2003
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 278 (26) , 23398-23409
- https://doi.org/10.1074/jbc.m302895200
Abstract
No abstract availableKeywords
This publication has 48 references indexed in Scilit:
- Exosites 1 and 2 Are Essential for Protection of Fibrin-bound Thrombin from Heparin-catalyzed Inhibition by Antithrombin and Heparin Cofactor IIJournal of Biological Chemistry, 1999
- Investigation of the Anticoagulant Mechanisms of a Covalent Antithrombin-Heparin ComplexJournal of Biological Chemistry, 1998
- Mechanism of Heparin Activation of Antithrombin: Evidence for an Induced-Fit Model of Allosteric Activation Involving Two Interaction SubsitesBiochemistry, 1998
- Polypeptide-Polysaccharide Conjugates Produced by Spontaneous Non-Enzymatic GlycationThe Journal of Biochemistry, 1998
- Sulfhydryls associated with H2O2-induced channel activation are on luminal side of ryanodine receptorsAmerican Journal of Physiology-Cell Physiology, 1998
- Mechanism of Heparin Activation of AntithrombinJournal of Biological Chemistry, 1998
- Covalent Antithrombin-Heparin Complexes with High Anticoagulant ActivityJournal of Biological Chemistry, 1997
- Mechanism of thrombin inactivation by immobilized heparinJournal of Biomedical Materials Research, 1996
- Electrostatic interactions in the heparin-enhanced reaction between human thrombin and antithrombinBiochemical Journal, 1983
- Molecular weight dependency of the heparin potentiated inhibition of thrombin and activated factor X. Effect of heparin neutralization in plasmaThrombosis Research, 1979