U.v. wavelength dependence for the induction of ornithine decarboxylase activity in hairless mouse epidermis
- 1 January 1986
- journal article
- research article
- Published by Oxford University Press (OUP) in Carcinogenesis: Integrative Cancer Research
- Vol. 7 (4) , 601-604
- https://doi.org/10.1093/carcin/7.4.601
Abstract
Induction of mouse epidermal ornithine decarboxylase activity by u.v. radiation has been studied with a monochromator. Dose-response studies were carried out with 10 nm increments between 260 and 320 nm. Time-course studies were carried out at 280, 290 and 300 nm. Ornithine decarboxylase activity, assessed at 24 h post-irradiation, was induced in a dosedependent fashion between 260 and 310 nm with peak activity at 280–290 nm. These data suggest that the chromophore is a protein.Keywords
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