An Individual with Hb‐Lepore‐Baltimore‐ δβ‐Thalassaemia in a Yugoslavian Family

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Abstract
The clinical, haematological and biochemical findings in a person with δβ‐thalassaemia and Hb‐Lepore are described. The patient was a 24‐year‐old student who suffered from anaemia of intermediate seventy with late onset of the clinical manifestations, had minor bone and facial deformities, but had no necessity for regular transfusions. Haemoglobins A and A2 were absent in this individual, and the Hb‐Lepore has been identified as Lepore‐Baltimore. Heterogeneity of γ chain of the Hb‐F follows the expected pattern. The study provides further evidence that neither β nor δ chains are synthesized in cis to δβ‐thalassaemia or Hb‐Lepore.