Pulling Pinned Polymers and Unzipping DNA
- 14 August 2000
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 85 (7) , 1572-1575
- https://doi.org/10.1103/physrevlett.85.1572
Abstract
We study a class of micromanipulation experiments, exemplified by the pulling apart of the two strands of double-stranded DNA. When the pulling force is increased to a critical value, an “unzipping” transition occurs. For random DNA sequences with short-ranged correlations, we obtain exact results for the number of monomers liberated and the specific heat, including the critical behavior at the transition. Related systems include a random heteropolymer pulled away from an adsorbing surface and a vortex line in a type II superconductor tilted away from a fragmented columnar defect.Keywords
All Related Versions
This publication has 39 references indexed in Scilit:
- Energy landscapes of receptor–ligand bonds explored with dynamic force spectroscopyNature, 1999
- Reversible Unfolding of Individual Titin Immunoglobulin Domains by AFMScience, 1997
- Folding-Unfolding Transitions in Single Titin Molecules Characterized with Laser TweezersScience, 1997
- Elasticity and unfolding of single molecules of the giant muscle protein titinNature, 1997
- The Elasticity of a Single Supercoiled DNA MoleculeScience, 1996
- Overstretching B-DNA: The Elastic Response of Individual Double-Stranded and Single-Stranded DNA MoleculesScience, 1996
- DNA: An Extensible MoleculeScience, 1996
- Intermolecular Forces and Energies Between Ligands and ReceptorsScience, 1994
- Adhesion Forces Between Individual Ligand-Receptor PairsScience, 1994
- Direct Mechanical Measurements of the Elasticity of Single DNA Molecules by Using Magnetic BeadsScience, 1992