Occurrence of octadecenoic fatty acid isomers from hydrogenated fats in human tissue lipid classes
- 1 August 1982
- Vol. 17 (8) , 551-557
- https://doi.org/10.1007/bf02535383
Abstract
The level oftrans-18∶1 isomers in several isolated lipid classes of human liver, heart, red blood cells and plasma was determined. Phospholipids contained substantially fewertrans-18∶1 isomers than triglycerides. The double bond distribution of thecis andtrans octadecenoate fraction of triglycerides and phosphatidylcholines from human liver and heart was determined. Whereas the double bond distribution of the triglycerides correlated closely with the pattern found in dietary hydrogenated vegetable oils, the phosphatidylcholine fraction showed evidence of selective incorporation or metabolism of specifictrans positional isomers. In general, isomers with double bonds near the methyl terminus were present at levels higher than expected from their relative abundance in the diet. Refinements in methodology needed to analyze octadecenoate double bond configuration and location in human tissues are presented.This publication has 24 references indexed in Scilit:
- Metabolic aspects of positional monounsaturated fatty acids isomersJournal of Oil & Fat Industries, 1981
- Incorporation of positional isomers of cis- and tnans-octadecenoic acids into acyl moieties of rat tissue lipidsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1979
- Rapid, large-scale purification of crude egg phospholipids using radially compressed silica gel columnsJournal of Chromatography A, 1978
- Occurrence of individual trans-isomeric fatty acids in human myocardium, jejunum and aorta in relation to different degrees of atherosclerosisAtherosclerosis, 1977
- Identification of thetrans isomers of octadecenoic acid in human milkLipids, 1977
- Trans-Unsaturated Fatty Acids In Human Skin Surface LipidsJournal of Investigative Dermatology, 1976
- Fat in today's food supply—Level of use and sourcesJournal of Oil & Fat Industries, 1974
- Evaluation of a gas chromatogram of a mixture containing aldehydes and aldehydic esters obtained by oxidative degradation of the positional isomers of methyl octadecenoateJournal of Oil & Fat Industries, 1972
- Fatty acids, part 16. Thin layer and gas—liquid chromatographic properties of the cis and trans methyl octadecenoates and of some acetylenic estersChemistry and Physics of Lipids, 1967
- The hydrogenation of dietary unsaturated fatty acids by the ruminantJournal of Oil & Fat Industries, 1956