The effect of X-rays on the glucose and hexose-phosphate glycolysis of tumour tissue
Open Access
- 18 May 1939
- journal article
- research article
- Published by The Royal Society in Proceedings of the Royal Society of London. B. Biological Sciences
- Vol. 127 (847) , 223-237
- https://doi.org/10.1098/rspb.1939.0019
Abstract
Radiation of tumor tissue at 0[degree] C. by [chi] or [gamma] rays inhibited the activity of the tissue in forming lactic acid from glucose. A dose of [chi]-radiation sufficient to inhibit the breakdown of glucose by the tissue, had no effect on the formation of lactic acid from hexose di- or mono-phosphate or glucose-1-phosphate (Cori ester). The decrease in activity of the dehydroglucose system in young embryonic brains, which was caused by irradiation, was corrected completely or partly, by the addition of co-enzyme I to the tissue.This publication has 5 references indexed in Scilit:
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- Studies in tissue metabolismBiochemical Journal, 1938
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- Metabolism of tissues growing in culture. V. Effect of radium on the metabolism of cultures of embryonic kidney tissue.1933
- The delayed lethal effect of radium on tissue cultures in vitroProceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 1930