DILUTION CHARACTERISTICS OF COOMASSIE BLUE IN MAN

Abstract
The dye Coomassie Blue has been studied in 17 patients, after injection alone, and together with radio-iodinated human serum albumin. Evidence has been presented to indicate that Coomassie Blue remains intravascular during its first transit through the lesser circulation. There is, however, a substantial early extravascular escape of the dye and this invalidates its use for plasma volume measurement by the usual methods.