Experience With a Metered-Dose Inhaler With a Spacer in the Pediatric Emergency Department
- 1 June 1989
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Pediatrics & Adolescent Medicine
- Vol. 143 (6) , 678-681
- https://doi.org/10.1001/archpedi.1989.02150180056020
Abstract
• Studies of adults suggest that metered-dose inhalers with spacers are as effective as hand-held nebulizers for bronchodilator delivery. We studied 13 children with acute asthma. They received two puffs every 2 minutes from metereddose inhalers with spacers (range, 4 to 14 puffs) titrated until improvement stopped. Peak expiratory flow increased 34% for metered-dose inhalers with spacers after the first 2 puffs and increased 87% for metered-dose inhalers with spacers after dose titration. After titration, respiratory rate decreased by 12%, heart rate increased by 2%, and breath sounds improved in 92% of the patients. We concluded that the metered-dose inhalers with spacers are an effective device for the treatment of asthma in the pediatric emergency department and that the use of metered-dose inhalers with spacers with titration can achieve significant bronchodilation in the treatment of patients with acute asthma. (AJDC. 1989;143:678-681)This publication has 13 references indexed in Scilit:
- Equivalence of Continuous Flow Nebulizer and Metered-Dose Inhaler with Reservoir Bag for Treatment of Acute Airflow ObstructionChest, 1988
- Cost-Benefit Comparison of Aerosol Bronchodilator Delivery Methods in Hospitalized PatientsChest, 1987
- Control of Asthma by AerosolsNew England Journal of Medicine, 1986
- Double-blind Crossover Study of Five Bronchodilator Medications and Two Delivery Methods in Stable AsthmaChest, 1986
- Comparison of Metered-Dose Inhaler Attached to an Aerochamber with an Updraft Nebulizer for the Administration of Metaproterenol in Hospitalized PatientsJournal of Asthma, 1985
- Comparison of three techniques of inhalation on the airway response to terbutaline.Thorax, 1983
- Salbutamol Inhalation in Chronic Asthma Bronchiale: Dose Aerosol vs Jet NebulizerChest, 1981
- Comparative efficacy of salbutamol by pressurized aerosol and wet nebulizer in acute asthma.British Journal of Clinical Pharmacology, 1980
- Effect of lung function and mode of inhalation on penetration of aerosol into the human lung.Thorax, 1977
- Dose-response effects of albuterol aerosol compared with isoproterenol and placebo aerosols *1, *2Response to albuterol, isoproterenol, and placebo aerosolsJournal of Allergy and Clinical Immunology, 1977