Dropspots: a picoliter array in a microfluidic device
- 28 October 2008
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Lab on a Chip
- Vol. 9 (1) , 44-49
- https://doi.org/10.1039/b809670h
Abstract
We present a simple microfluidic device that uses an array of well-defined chambers to immobilize thousands of femtoliter- to picoliter-scale aqueous drops suspended in inert carrier oil. This device enables timelapse studies of large numbers of individual drops, while simultaneously enabling subsequent drop recovery.Keywords
This publication has 24 references indexed in Scilit:
- Nanoliter Reactors Improve Multiple Displacement Amplification of Genomes from Single CellsPLoS Genetics, 2007
- Reactions in Droplets in Microfluidic ChannelsAngewandte Chemie International Edition in English, 2006
- Phenotypic heterogeneity can enhance rare‐cell survival in ‘stress‐sensitive’ yeast populationsMolecular Microbiology, 2006
- Microbial cell individuality and the underlying sources of heterogeneityNature Reviews Microbiology, 2006
- Electrocoalescence of drops synchronized by size-dependent flow in microfluidic channelsApplied Physics Letters, 2006
- A microengraving method for rapid selection of single cells producing antigen-specific antibodiesNature Biotechnology, 2006
- Stochastic protein expression in individual cells at the single molecule levelNature, 2006
- Noise in Gene Expression: Origins, Consequences, and ControlScience, 2005
- Bacterial Persistence as a Phenotypic SwitchScience, 2004
- Formation of dispersions using “flow focusing” in microchannelsApplied Physics Letters, 2003