Induction of hemopoietic chimerism in the caprine fetus by intraperitoneal injection of fetal liver cells
- 1 March 1989
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 45 (3) , 307-308
- https://doi.org/10.1007/bf01951819
Abstract
Intraperitoneal injection of allogeneic liver cells from 43-day-old male fetuses into normal 60-day female goat fetuses resulted in persistent hemopoietic chimerism in surviving recipients without clinical evidence of graft-versus-host disease. Transplantation of normal fetal liver cells into preimmunocompetent goat fetuses affected with β-D-mannosidosis may provide an alternative strategy for evaluating hemopoietic stem cell transplantation in the treatment of human lysosomal storage diseases.This publication has 13 references indexed in Scilit:
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