Identification of negative regulatory genes that govern the expression of early meiotic genes in yeast.
- 1 December 1989
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 86 (24) , 10018-10022
- https://doi.org/10.1073/pnas.86.24.10018
Abstract
Mutations in Saccharomyces cerevisiae have been identified that derepress early meiotic genes functioning in separable pathways required for normal meiotic development. The phenotypes of these ume (unscheduled meiotic gene expression) mutations suggest that their wild-type alleles encode negative regulators acting downstream of both the cell-type and nutritional controls of meiosis. These newly defined loci do not affect either general transcripton or transcription of meiotic genes expressed later in meiosis and spore formation.This publication has 29 references indexed in Scilit:
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