Studies on the substrate for hepatic lipogenesis in the rat
- 17 September 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 175 (1) , 8-12
- https://doi.org/10.1016/0014-5793(84)80558-x
Abstract
The contribution of hepatic glycogen to lipogenesis was studied in isolated, intact rat hepatocytes. To establish its importance as a substrate for lipogenesis, the glycogen of isolated hepatocytes was prelabelled with 14C from glucose. Evidence is presented that neither glucose nor glycogen constitute major sources of carbon for de novo synthesis of fatty acids and that less than 1 % of glycogen is converted into fatty acidsKeywords
This publication has 22 references indexed in Scilit:
- Acetoacetate: a major substrate for the synthesis of cholesterol and fatty acids by isolated rat hepatocytesFEBS Letters, 1983
- Short-term Hormonal Control of Hepatic LipogenesisDiabetes, 1980
- A Molecular Order in the Synthesis and Degradation of Glycogen in the LiverEuropean Journal of Biochemistry, 1979
- Short‐term effects of insulin and glucagon on lipid synthesis in isolated rat hepatocytesFEBS Letters, 1978
- Heterogeneous distribution of glucose‐6‐phosphatase in microdissected periportal and perivenous rat liver tissueFEBS Letters, 1977
- Restoration of glycogenesis in hepatocytes from starved ratsLife Sciences, 1977
- Chapter 4 Preparation of Isolated Rat Liver CellsPublished by Elsevier ,1976
- Autoregulation of glycolysis, respiration, gluconeogenesis and glycogen synthesis in isolated parenchymal rat liver cells under aerobic and anaerobic conditionsBiochimica et Biophysica Acta (BBA) - General Subjects, 1974
- Enzymatic Interconversion of Active and Inactive Forms of EnzymesScience, 1973
- [7] Chemical procedures for analysis of polysaccharidesPublished by Elsevier ,1957