DISTRIBUTION OF GONADOTROPHIC AND ADRENOCORTICOTROPHIC ACTIVITY IN THE ANTERIOR PITUITARY GLAND OF THE MALE RAT1

Abstract
Gonadotrophic and ACTH activity were assayed in a segment of the pituitary rich in peripheral gonadotrophs (delta cells) and in an area almost devoid of this type of cell. The region rich in delta cells was found to contain three times the gonadotrophic activity and one-third the ACTH activity of the region poor in delta cells. Thus the delta cells are the site of gonadotrophin and not of ACTH production.