Abstract
Populations of Chironomus tentans from Iowa and Wisconsin show consistent polymorphisms for inversion sequences of chromosome 1 which are associated with sex. Male larvae from Iowa populations are invariably heterozygous for a sequence of the left arm which is never present in females. In a Wisconsin population, however, females are consistently heterozygous for a dominant sex factor, female determiner (Fd), linked to but not inseparable from an inversion sequence of the right arm. Two primary loci for sex determination appear to have evolved different dominance relations in these races.