Blockade of glutamate mGlu5 receptors in a rat model of neuropathic pain prevents early over-expression of pro-apoptotic genes and morphological changes in dorsal horn lamina II
- 21 January 2004
- journal article
- research article
- Published by Elsevier in Neuropharmacology
- Vol. 46 (4) , 468-479
- https://doi.org/10.1016/j.neuropharm.2003.10.014
Abstract
No abstract availableKeywords
This publication has 44 references indexed in Scilit:
- [3H]Methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine Binding to Metabotropic Glutamate Receptor Subtype 5 in Rodent Brain: In Vitro and in Vivo CharacterizationThe Journal of Pharmacology and Experimental Therapeutics, 2002
- Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotectiveNeuropharmacology, 2000
- Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR5) antagonist, in experimental neuropathic pain in ratsNeuroscience Letters, 2000
- Neurodegeneration inLurcherMice Occurs via Multiple Cell Death PathwaysJournal of Neuroscience, 2000
- Transgenic expression of TNF by astrocytes increases mechanical allodynia in a mouse neuropathy modelNeuroReport, 2000
- Peripheral nerve insult induces NMDA receptor-mediated, delayed degeneration in spinal neuronsEuropean Journal of Neuroscience, 1998
- The pharmacology of excitatory and inhibitory amino acid-mediated events in the transmission and modulation of pain in the spinal cordGeneral Pharmacology: The Vascular System, 1997
- Exposure of rat spinal neurones to NMDA, AMPA and kainate produces only short-term enhancements of responses to noxious and non-noxious stimuliNeuroscience Letters, 1994
- A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in manPain, 1988
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976