Partial non-cleavage by cyanogen bromide of a methionine–cystine bond from human serum albumin and bovine α-lactalbumin
- 1 January 1979
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 177 (1) , 251-254
- https://doi.org/10.1042/bj1770251
Abstract
When human albumin was treated with CNBr, a fragment designated D was obtained and attributed to the absence from some of the albumin molecules of methionine at position 123 [Lapresle & Doyen (1975) Biochem. J. 151, 637-643]. The present study shows that methionine-123 is converted into homoserine without cleavage of the subsequent methionine-cystine bond. With bovine alpha-lactalbumin, a further example of non-cleavage of a methionine-cystine bond with conversion of methionine into homoserine is reported.This publication has 13 references indexed in Scilit:
- Complete amino acid sequence of human serum albuminPublished by Wiley ,2001
- Semisynthetic analogues of insulin. The use of N-substituted derivatives of methionine as acid-stable protecting groupsBiochemical Journal, 1977
- Isolation and properties of a fragment of human serum albumin demonstrating the absence of a methionine residue from some of the albumin moleculesBiochemical Journal, 1975
- Cyanogen bromide treatment of N-acetylmethionyl residues without cleavageBiochemistry, 1974
- Cleavage of cytochrome c with cyanogen bromideBiochimica et Biophysica Acta (BBA) - Protein Structure, 1970
- The Isolation and Characterization of the Tryptic, Chymotryptic, Peptic, and Cyanogen Bromide Peptides from Bovine α-LactalbuminJournal of Biological Chemistry, 1970
- The Complete Amino Acid Sequence of Bovine α-LactalbuminJournal of Biological Chemistry, 1970
- An examination of conditions for the cleavage of polypeptide chains with cyanogen bromide: Application to catalaseArchives of Biochemistry and Biophysics, 1969
- The covalent structure of a human γG-immunoglobulin. V. Partial amino acid sequence of the light chainBiochemistry, 1968
- The amino acid sequence of cytochrome C from Candida krusei.1968