Protective effect of nicotinamide on bracken fern induced carcinogenicity in rats
- 1 January 1981
- journal article
- other
- Published by Taylor & Francis in Nutrition and Cancer
- Vol. 3 (2) , 86-93
- https://doi.org/10.1080/01635588109513707
Abstract
Albino noninbred weanling male and female rats were fed a basic grain diet (Group I), a basic diet supplemented with 0.5% nicotinamide (Group 2), a basic diet containing 33 % bracken fern (BF) (Group 3), or a basic diet supplemented with 33 % BF and 0.5% nicotinamide (Group 4) for 58 weeks. Dietary nicotinamide decreased the BF‐induced incidence of both intestinal and bladder tumorigenesis by about 40%. The inhibitory effect of nicotinamide on the BF‐induced intestinal and bladder tumors was significant at p< 0.05 and p < 0.07, respectively.Keywords
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