Histone Proteins in HeLa S 3 Cells Are Synthesized in a Cell Cycle Stage Specific Manner
- 5 February 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 215 (4533) , 683-685
- https://doi.org/10.1126/science.7058333
Abstract
The synthesis of histone proteins in G1 and S phase HeLa S3 cells was examined by two-dimensional electrophoretic fractionation of nuclear and total cellular proteins. Newly synthesized histones were detected only in S phase cells. Histone messenger RNA sequences, as detected by hybridization with cloned human histone genes, were present in the cytoplasm of S phase but not G1 cells.This publication has 22 references indexed in Scilit:
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