The yeastADR6gene encodes homopolymeric amino acid sequences and a potential metal-binding domain
- 1 January 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 16 (21) , 10153-10169
- https://doi.org/10.1093/nar/16.21.10153
Abstract
The ADR6 gene of Saccharomyces cerevisiae has an open reading frame which could encode a polypeptide of 1314 amino acids. The predicted mRNA encodes a protein with homopolymeric stretches of asparagine and threonine, particularly near its amino terminus and contains additional sequences consisting of polyglutamine repeats. The predicted protein also contains a potential metal binding (Cys)4-type finger near its carboxy-terminus. An ADR6/.beta.-galactosidase fusion protein was predominantly nuclear in location, consistent with its role as an activator of ADH2 transcription.This publication has 97 references indexed in Scilit:
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