Macrophage Tumor Killing: Influence of the Local Environment
- 15 July 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 197 (4300) , 279-282
- https://doi.org/10.1126/science.327547
Abstract
Tumor killing by activated macrophages is not a highly determined biologic event, but a relative capability influenced by the local environment. An intrinsic macrophage cytotoxic effector system is modulated by serum and other environmental factors that can either enhance or suppress tumor killing. Activated macrophages kill tumor cells only when a regulating threshold drops to a critically low level.This publication has 19 references indexed in Scilit:
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