SUCCINIC DEHYDROGENASE IN RAT OVARIAN TISSUES DURING PREGNANCY AND LACTATION1,2

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Abstract
The suc-cinic dehydrogenase of the corpora lutea of rats increases rapidly in cone, from day 4 to a maximum at 11th day of pregnancy, remains constant to day 20 and decreases rapidly to low levels after parturition. The wt. of the corpora does not begin to increase rapidly until the 11th day, reaches a maximum between days 15 and 20 followed by a rapid decrease after parturition. The enzyme of the corpora of the post partum ovulation increases in cone, from the 4th day to a maximum at the 20th day of lactation at which time the ac- tivity is greater than that found at any time for the corpora of pregnancy. The wt. of the corpora of the post partum ovulation changes little during lactation. The succinic de-hydrogenase activity of the ovarian residue varies little during pregnancy and Jactation. The cytochrome oxidase cone, was much higher in the corpora at the 11th and 20th days of pregnancy than during diestrus. The changes in the conc. of succinic dehydrogenase are discussed in relation to the function of the corpora during pregnancy and lactation.