HLA Compatibility in Couples with Children Suffering from Acute Leukemia or Aplastic Anemia

Abstract
The frequency of common HLA-A and -B antigens was determined in 30 couples having a child with acute leukemia (AL), 34 couples having a child with aplastic anemia (AA) and 58 random couples with healthy children. An increased frequency of couples sharing at least 2 common antigens was observed in parents of AL and AA children.