Comparison of the pregnancy-associated murine protein-2 and human pregnancy-specific 1-glycoprotein
- 1 September 1980
- journal article
- research article
- Published by Bioscientifica in Reproduction
- Vol. 60 (1) , 115-119
- https://doi.org/10.1530/jrf.0.0600115
Abstract
Immunological cross-reaction between human pregnancy-specific .beta.1-glycoprotein (SP-1) and pregnancy-associated murine protein-2 (PAMP-2) was demonstrated by line immunoelectrophoresis using antibodies against the proteins raised in hens. The pattern of change of PAMP-2 and SP-1 values in serum during pregnancy was very similar. The murine placental growth-rate corresponded to PAMP-2 levels in maternal serum during pregnancy, indicating placental origin. Apparently, the mouse and its PAMP-2 can be used to study human SP-1.Keywords
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