Synthesis of 3-(1-Adamantyl)pyrazole and 3,5-Di(1-adamantyl)pyrazole in a Microwave Oven
- 1 November 1994
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 23 (11) , 2079-2080
- https://doi.org/10.1246/cl.1994.2079
Abstract
An extraordinary inversion of the regioselectivity in the reaction of C-adamantylation of pyrazoles by 1-bromoadamantane was observed when the autoclave vessel was replaced by a microwave oven. In these last conditions mono and disubstituted 3(5)-(1-adamantyl) pyrazoles were obtained.Keywords
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