Sensitivity ofHartmannella(Acanthamoeba) to5-fluorocytosine, hydroxystilbamidine, and other substances
Open Access
- 1 November 1970
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 23 (8) , 649-652
- https://doi.org/10.1136/jcp.23.8.649
Abstract
The effect of 24 anti-amoebic and other chemotherapeutic compounds on six strains of hartmannellid amoebae was studied by tissue culture, agar diffusion, and liquid axenic culture. Of the recognized anti-amoebic compounds only one inhibited growth of the amoebae, which were remarkable for their resistance. Two compounds, hydroxystilbamidine isethionate and 5-fluorocytosine, showed some amoebicidal activity while some others were inhibitory.Keywords
This publication has 11 references indexed in Scilit:
- Two Cases of Cryptococcal Meningitis, one Treated with 5-FluorocytosineBMJ, 1969
- Sensitivity to amphotericin B of aNaegleriasp. isolated from a case of primary amoebic meningoencephalitisJournal of Clinical Pathology, 1969
- Primary amoebic meningo‐encephalitis: Clinical, pathological and epidemiological features of six fatal casesThe Journal of Pathology and Bacteriology, 1968
- Study of a Small Amoeba from Mammalian Cell Cultures Infected with "Ryan Virus'Journal of General Microbiology, 1968
- A Divided Petri Dish for Use with Multipoint InoculatorsJournal of Applied Bacteriology, 1967
- Re‐Definition of the Genus Acanthamoeba with Descriptions of Three SpeciesThe Journal of Protozoology, 1967
- Taxonomic Criteria for Limax Amoebae, with Descriptions of 3 New Species of Hartmannella and 3 of Vahlkampfia*The Journal of Protozoology, 1967
- A Comparative Study of Hartmannellid AmoebaeThe Journal of Protozoology, 1964
- Purification, Axenic Cultivation, and Description of a Soil Amoeba, Acanthamoeba sp.The Journal of Protozoology, 1957
- SECTION OF BIOLOGY*: PHARMACOLOGY AND THERAPEUTIC VALUE OF DIAMIDINE DERIVATIVES—PARTICULARLY OF 2‐HYDROXYSTILBAMIDINE†Transactions of the New York Academy of Sciences, 1952