Ontogenetic changes in the concentration of serum proteins in chick and mammalian embryos

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Abstract
It is generally recognized, on the basis of electrophoretic studies, that the serum proteins of individuals in the perinatal period of development are somewhat different than those of the adult (Kekwick, 1959; Lehrer & Toben, 1965). It is also known that the protein content of the serum of perinatal mammals is low, and gradually rises to the adult level over a period of weeks or months (McMurray, Roe & Sweet, 1948; Knapp & Routh, 1949; Ewerbeck & Levens, 1950; Potter, 1952; Halliday & Kekwick, 1957). Virtually nothing, however, is known about the serum proteins of very young vertebrate embryos, presumably because of technical difficulties involved in obtaining samples suitable for quantitative study.