A CHEMICALLY DEFINED MEDIUM FOR THE GROWTH OF CEPHALOSPORIUM SALMOSYNNEMATUM

Abstract
A chemically defined medium was developed which supplied the nutritional requirements of Cephalosporium salmosynnematum. A yield of dry mycelium of 6.78 g was obtained from 10 g of glucose and 5 g of L-glutamic acid present in one liter of medium. The organism required organic nitrogen for maximum yield. A variety of amino acids provided the nitrogen and served as carbon source. L-Glutamic acid gave the highest yields of mycelium. The following minerals were essential for growth: K, Mg, S, P, Zn, Fe and Cu. Vitamins were not required. Analytical data indicated that while organic nitrogen was preferred, some NH3N was utilized.