Morbidity of Nonfebrile Status Epilepticus in Rochester, Minnesota, 1965–1984

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Abstract
Summary: Purpose: To analyze the nonfatal adverse events (AE) associated with a first episode of status epilepticus (SE). Methods: We performed a population‐based retrospective cohort study to determine the morbidity of SE. Participants included 184 residents of Rochester, Minnesota who experienced nonfebrile SE between 1965 and 1984. Results: The etiology of SE was acute symptomatic in 100 patients and unprovoked in 84 patients. The most common seizure‐types were continuous partial (n = 56, 30%), generalized convulsive (n = 52, 28%). and generalized with focal features (n = 32, 17%). Morbidity related to SE was noted in 5 of the 146 patients (3.4%) surviving 30 days. The AE included hemiparesis (n = 3), encephalopathy (n = 2), mental retardation (n = l), and aphasia (n = 1). All patients with morbidity had an acute symptomatic (n = 4) or remote symptomatic (n = 1) etiology. Thirty‐four patients (18.5%) had a second episode of SE. Conclusions: Based on this retrospective study, significant morbidity related to SE is uncommon and is associated with the underlying etiology.