Chlorpromazine Disposition in Relation to Age in Children
- 1 April 1990
- journal article
- research article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 18 (4) , 329-331
- https://doi.org/10.2165/00003088-199018040-00005
Abstract
The pharmacokinetics of chlorpromazine after intravenous infusion were studied in 25 children. The pharmacokinetic parameters studied are markedly different from those reported for adults. A clear relationship was demonstrated between age, serum terminal half-life (r = 0.75) and systemic clearance (r = -0.43). It appears that the pharmacokinetics of chlorpromazine are more rapid in children than in adults.This publication has 7 references indexed in Scilit:
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