In Vivo Uptake of Cations by Two Types of Exchange Resins

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Abstract
The effects of sulfonic and carboxylic exchangers on cation metabolism were studied in rats. The resins increased the fecal output of Na by about 0.8-1.0 meq., K and Ca about 04 meq., and Mg about 0.3 meq., per g. ingested. Both types were apparently excreted in combination with some ammonium and H ions. Neither type of resin significantly increased the fecal excretion of Fe, amino N, thiamine, or riboflavin. Studies based on feeding different proportions of the sulfonic resin in the Na or K cycle indicated that there is no disturbance of acid-base balance when the resin contains 2.4 meq. of fixed base per g. This is taken to mean that the total effective cation uptake is 2.4 meq./g.
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