Changes of Pharmacokinetics and Metabolism of Sulfadimidine in Endotoxin Pretreated Rabbits
- 1 January 1980
- book chapter
- Published by Springer Nature
- Vol. 4, 325-327
- https://doi.org/10.1007/978-3-642-67729-8_67
Abstract
Changes of pharmacokinetics and acetylation of sulfadimidine (SDM) were studied in endotoxin pretreated rabbits. With increasing doses of endotoxin the levels of intravenously administered SDM were lower. The acetylation rate was reduced in urine of rabbits after medium endotoxin doses.Keywords
This publication has 1 reference indexed in Scilit:
- Pharmacokinetics of Trimethoprim (TMP) in Normal and Febrile RabbitsActa Pharmacologica et Toxicologica, 1977