Detection of a leukocytic endogenous mediator-like mediator of serum amino acid and zinc depression during various infectious illnesses

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Abstract
Serum samples from patients with many different kinds of infection were shown to contain a substance characteristic of leukocytic endogenous mediator. Generalized bacterial infections produced more leukocytic endogenous mediator than did localized ones; viral infections produced very little. In typhoid fever, mediator concentrations increased before the onset of illness.